The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis

Ruixiang Yang; Yue Zhou; Tongjia Zhang; Shujie Wang; Jiyin Wang; Yuning Cheng; Hui Li; Wei Jiang; Zhe Yang; Xiaowei Zhang

doi:10.1371/journal.pbio.3001862

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Open Access

Peer-reviewed

Research Article

The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis

Ruixiang Yang,

Roles Investigation

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Yue Zhou,

Roles Methodology

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Tongjia Zhang,

Roles Data curation, Software

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Shujie Wang,

Roles Methodology

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Jiyin Wang,

Roles Formal analysis

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Yuning Cheng,

Roles Software

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Hui Li,

Roles Validation

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Wei Jiang,

Roles Visualization

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China
⨯
Zhe Yang,

Roles Software

Affiliation Department of pathology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China
⨯
Xiaowei Zhang

Roles Writing – review & editing

* E-mail: xiaoweizhang@bjmu.edu.cn.

Affiliation Department of Biochemistry and Biophysics, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Peking University Health Science Center, Beijing, China

https://orcid.org/0000-0001-7280-2844

⨯

The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis

Ruixiang Yang,
Yue Zhou,
Tongjia Zhang,
Shujie Wang,
Jiyin Wang,
Yuning Cheng,
Hui Li,
Wei Jiang,
Zhe Yang,
Xiaowei Zhang

Published: July 5, 2023
https://doi.org/10.1371/journal.pbio.3001862

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