Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Qiannan Deng; Cheng Wang; Chwee Tat Koe; Jan Peter Heinen; Ye Sing Tan; Song Li; Cayetano Gonzalez; Wing-Kin Sung; Hongyan Wang

doi:10.1371/journal.pbio.3001834

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Open Access

Peer-reviewed

Research Article

Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Qiannan Deng,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore
⨯
Cheng Wang,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore
⨯
Chwee Tat Koe,

Roles Data curation, Formal analysis, Methodology

Current address: Genome Institute of Singapore, Genome, Singapore

Affiliation Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore
⨯
Jan Peter Heinen,

Roles Data curation, Formal analysis, Methodology

Affiliation Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain
⨯
Ye Sing Tan,

Roles Data curation, Formal analysis, Methodology

Affiliation Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore
⨯
Song Li,

Roles Data curation, Formal analysis, Methodology

Affiliation Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore
⨯
Cayetano Gonzalez,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain, Institució Catalana de Recerca i Estudis Avançats, ICREA, Barcelona, Spain
⨯
Wing-Kin Sung,

Roles Data curation, Formal analysis, Methodology

Affiliations Genome Institute of Singapore, Genome, Singapore, Department of Computer Science, National University of Singapore, Singapore
⨯
Hongyan Wang

Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: hongyan.wang@duke-nus.edu.sg

Affiliations Neuroscience & Behavioral Disorders Programme, Duke-NUS Medical School, Singapore, Dept. of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, NUS Graduate School—Integrative Sciences and Engineering Programme (ISEP), National University of Singapore, Singapore

https://orcid.org/0000-0003-4623-1878

⨯

Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Qiannan Deng,
Cheng Wang,
Chwee Tat Koe,
Jan Peter Heinen,
Ye Sing Tan,
Song Li,
Cayetano Gonzalez,
Wing-Kin Sung,
Hongyan Wang

Published: October 12, 2022
https://doi.org/10.1371/journal.pbio.3001834

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RNA interference
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Metaphase
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Centrosomes
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Larvae
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Drosophila melanogaster
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