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Open Access
Peer-reviewed
Research Article
Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease
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Faith M. Anderson ,
Contributed equally to this work with: Faith M. Anderson, Noelle D. Visser
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Noelle D. Visser ,
Contributed equally to this work with: Faith M. Anderson, Noelle D. Visser
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Current address: Department of Biology, University of Louisville, Louisville, Kentucky, United States of America
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Kevin R. Amses,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Current address: Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Affiliation Department of Ecology and Evolution, University of Michigan, Ann Arbor, Michigan, United States of America
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Andrea Hodgins-Davis,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Alexandra M. Weber,
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing
Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Katura M. Metzner,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Michael J. McFadden,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Ryan E. Mills,
Roles Formal analysis, Methodology, Software, Supervision, Writing – review & editing
Affiliations Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Matthew J. O’Meara,
Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Timothy Y. James,
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing
Affiliation Department of Ecology and Evolution, University of Michigan, Ann Arbor, Michigan, United States of America
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Teresa R. O’Meara
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: tromeara@umich.edu
Affiliation Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease
- Faith M. Anderson,
- Noelle D. Visser,
- Kevin R. Amses,
- Andrea Hodgins-Davis,
- Alexandra M. Weber,
- Katura M. Metzner,
- Michael J. McFadden,
- Ryan E. Mills,
- Matthew J. O’Meara,
- Timothy Y. James
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- Published: May 19, 2023
- https://doi.org/10.1371/journal.pbio.3001822