Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way

Arad Soffer; Adnan Mahly; Krishnanand Padmanabhan; Jonathan Cohen; Orit Adir; Eidan Loushi; Yaron Fuchs; Scott E. Williams; Chen Luxenburg

doi:10.1371/journal.pbio.3001756

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Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way

Arad Soffer,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Adnan Mahly,

Roles Data curation

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Krishnanand Padmanabhan,

Roles Data curation

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

https://orcid.org/0000-0002-5567-5051

⨯
Jonathan Cohen,

Roles Conceptualization

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

https://orcid.org/0000-0002-5920-5196

⨯
Orit Adir,

Roles Data curation

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

https://orcid.org/0000-0003-0918-6262

⨯
Eidan Loushi,

Roles Resources

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Yaron Fuchs,

Roles Conceptualization

Affiliation Department of Biology, Technion—Israel Institute of Technology, Haifa, Israel

https://orcid.org/0000-0003-4391-9386

⨯
Scott E. Williams,

Roles Conceptualization, Funding acquisition

Affiliation Departments of Pathology & Laboratory Medicine and Biology, Lineberger Comprehensive Cancer Center, The University of North Carolina, Chapel Hill, North Carolina, United States of America

https://orcid.org/0000-0001-9975-7334

⨯
Chen Luxenburg

Roles Conceptualization, Funding acquisition, Writing – original draft

* E-mail: lux@tauex.tau.ac.il

Affiliation Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

https://orcid.org/0000-0002-7801-3499

⨯

Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way

Arad Soffer,
Adnan Mahly,
Krishnanand Padmanabhan,
Jonathan Cohen,
Orit Adir,
Eidan Loushi,
Yaron Fuchs,
Scott E. Williams,
Chen Luxenburg

Published: August 15, 2022
https://doi.org/10.1371/journal.pbio.3001756

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Epidermis
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Apoptosis
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Integrins
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Cell cycle and cell division
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Keratinocytes
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Keratins
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DAPI staining
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Nuclear staining
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