Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B

• Mengqiu Jiang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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• Joonyoung Shin,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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• Rudo Simeon,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, Texas, United States of America

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• Jeng-Yih Chang,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

  https://orcid.org/0000-0003-3475-4508

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• Ran Meng,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

  https://orcid.org/0000-0003-1271-3975

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• Yuhang Wang,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

  https://orcid.org/0000-0002-8048-138X

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• Omkar Shinde,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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• Pingwei Li,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

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• Zhilei Chen,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, Texas, United States of America

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• Junjie Zhang

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: junjiez@tamu.edu

  Affiliation Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, United States of America

  https://orcid.org/0000-0002-7912-0819

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