A versatile new tool derived from a bacterial deubiquitylase to detect and purify ubiquitylated substrates and their interacting proteins

• Mengwen Zhang,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Chemistry, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0003-2703-211X

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• Jason M. Berk,

  Roles Conceptualization, Writing – review & editing

  Current address: Arvinas, Inc., New Haven, Connecticut, United States of America

  Affiliation Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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• Adrian B. Mehrtash,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

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• Jean Kanyo,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation W.M. Keck Foundation Biotechnology Resource Laboratory, Yale University, New Haven, Connecticut, United States of America

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• Mark Hochstrasser

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

  * E-mail: mark.hochstrasser@yale.edu

  Affiliations Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0002-1131-5484

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