LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains

• Jui-Hung Weng ,

  Contributed equally to this work with: Jui-Hung Weng, Phillip C. Aoto

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, California, United States of America

  https://orcid.org/0000-0002-0432-3515

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• Phillip C. Aoto ,

  Contributed equally to this work with: Jui-Hung Weng, Phillip C. Aoto

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, California, United States of America

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• Robin Lorenz,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

  https://orcid.org/0000-0002-6425-3790

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• Jian Wu,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, California, United States of America

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• Sven H. Schmidt,

  Roles Writing – review & editing

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

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• Jascha T. Manschwetus,

  Roles Writing – review & editing

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

  https://orcid.org/0000-0003-3136-9153

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• Pallavi Kaila-Sharma,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, University of California, San Diego, California, United States of America

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• Steve Silletti,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Department of Chemistry and Biochemistry, University of California, San Diego, California, United States of America

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• Sebastian Mathea,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Institute for Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany

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• Deep Chatterjee,

  Roles Resources

  Affiliation Institute for Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany

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• Stefan Knapp,

  Roles Writing – review & editing

  Affiliation Institute for Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany

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• Friedrich W. Herberg,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

  https://orcid.org/0000-0001-7117-7653

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• Susan S. Taylor

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: staylor@ucsd.edu

  Affiliation Department of Pharmacology, University of California, San Diego, California, United States of America

  https://orcid.org/0000-0002-7702-6108

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