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Open Access
Peer-reviewed
Research Article
Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus
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Fatima Amanat,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Shirin Strohmeier,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Philip S. Meade,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Nicholas Dambrauskas,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America
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Barbara Mühlemann,
Roles Data curation, Visualization, Writing – review & editing
Affiliations Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany, German Centre for Infection Research (DZIF), partner site Charité, Berlin, Germany
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Derek J. Smith,
Roles Data curation, Visualization, Writing – review & editing
Affiliation Centre for Pathogen Evolution, Department of Zoology, University of Cambridge, Cambridge, United Kingdom
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Vladimir Vigdorovich,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America
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D. Noah Sather,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, Washington, United States of America, Department of Pediatrics, University of Washington, Seattle, Washington, United States of America
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Lynda Coughlan,
Roles Investigation, Methodology, Writing – review & editing
Affiliations University of Maryland School of Medicine, Department of Microbiology and Immunology, Baltimore, Maryland, United States of America, University of Maryland School of Medicine, Center for Vaccine Development and Global Health (CVD), Baltimore, Maryland, United States of America
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Florian Krammer
Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
* E-mail: florian.krammer@mssm.edu
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus
- Fatima Amanat,
- Shirin Strohmeier,
- Philip S. Meade,
- Nicholas Dambrauskas,
- Barbara Mühlemann,
- Derek J. Smith,
- Vladimir Vigdorovich,
- D. Noah Sather,
- Lynda Coughlan,
- Florian Krammer
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- Published: December 16, 2021
- https://doi.org/10.1371/journal.pbio.3001384