The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting

• Andrew E. Shaw ,

  Contributed equally to this work with: Andrew E. Shaw, Suzannah J. Rihn, Nardus Mollentze

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliations MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom, The Pirbright Institute, Woking, United Kingdom

  https://orcid.org/0000-0001-5761-9769

  ⨯
• Suzannah J. Rihn ,

  Contributed equally to this work with: Andrew E. Shaw, Suzannah J. Rihn, Nardus Mollentze

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0001-9495-4056

  ⨯
• Nardus Mollentze ,

  Contributed equally to this work with: Andrew E. Shaw, Suzannah J. Rihn, Nardus Mollentze

  Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

  ¶‡ These authors share first authorship on this work.

  Affiliations MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom

  https://orcid.org/0000-0002-2452-6416

  ⨯
• Arthur Wickenhagen,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0001-5470-1505

  ⨯
• Douglas G. Stewart,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
• Richard J. Orton,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-3389-4325

  ⨯
• Srikeerthana Kuchi,

  Roles Methodology, Software, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
• Siddharth Bakshi,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
• Mila Rodriguez Collados,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-2304-6402

  ⨯
• Matthew L. Turnbull,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-7234-5871

  ⨯
• Joseph Busby,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
• Quan Gu,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-1201-6734

  ⨯
• Katherine Smollett,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0001-7961-7377

  ⨯
• Connor G. G. Bamford,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
• Elena Sugrue,

  Roles Investigation, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0001-5014-9522

  ⨯
• Paul C. D. Johnson,

  Roles Formal analysis, Writing – review & editing

  Affiliations MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom

  https://orcid.org/0000-0001-6663-7520

  ⨯
• Ana Filipe Da Silva,

  Roles Supervision, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-9442-2903

  ⨯
• Alfredo Castello,

  Roles Funding acquisition, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-1499-4662

  ⨯
• Daniel G. Streicker,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliations MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom

  https://orcid.org/0000-0001-7475-2705

  ⨯
• David L. Robertson,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0001-6338-0221

  ⨯
• Massimo Palmarini,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  ⨯
•  [ ... ],
• Sam J. Wilson

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Sam.Wilson@glasgow.ac.uk

  Affiliation MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow, United Kingdom

  https://orcid.org/0000-0002-6065-0895

  ⨯
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