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Open Access
Peer-reviewed
Research Article
IL-25–induced shifts in macrophage polarization promote development of beige fat and improve metabolic homeostasis in mice
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Lingyi Li ,
Contributed equally to this work with: Lingyi Li, Lei Ma, Zewei Zhao
Roles Conceptualization, Data curation, Methodology, Resources, Writing – original draft
Affiliations Department of Biochemistry, Molecular Cancer Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong Province, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Lei Ma ,
Contributed equally to this work with: Lingyi Li, Lei Ma, Zewei Zhao
Roles Conceptualization, Data curation, Formal analysis, Writing – original draft
Affiliations Department of Biochemistry, Molecular Cancer Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong Province, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Zewei Zhao ,
Contributed equally to this work with: Lingyi Li, Lei Ma, Zewei Zhao
Roles Conceptualization, Data curation, Formal analysis, Methodology
Affiliations Department of Biochemistry, Molecular Cancer Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong Province, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Shiya Luo,
Roles Data curation, Formal analysis, Methodology
Affiliation Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Baoyong Gong,
Roles Data curation, Formal analysis, Methodology
Affiliation Guangdong Provincial Key Laboratory of Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, Guangdong Province, China
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Jin Li,
Roles Data curation, Formal analysis
Affiliation Department of Gerontology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Juan Feng,
Roles Data curation, Formal analysis, Methodology
Affiliation School of Stomatology, Foshan University, Foshan, Guangdong Province, China
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Hui Zhang,
Roles Data curation, Formal analysis, Methodology
Affiliation Metabolic Innovation Center, Sun Yat-sen University, Guangzhou, Guangdong Province, China
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Weiwei Qi,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition
Affiliation Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Ti Zhou,
Roles Data curation, Formal analysis, Funding acquisition
Affiliation Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Xia Yang,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition
Affiliation Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Guoquan Gao,
Roles Conceptualization, Funding acquisition, Investigation, Supervision
Affiliation Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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Zhonghan Yang
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing
* E-mail: yangzhh@mail.sysu.edu.cn
Affiliations Department of Biochemistry, Molecular Cancer Research Center, School of Medicine, Sun Yat-sen University, Shenzhen, Guangdong Province, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong Province, China
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IL-25–induced shifts in macrophage polarization promote development of beige fat and improve metabolic homeostasis in mice
- Lingyi Li,
- Lei Ma,
- Zewei Zhao,
- Shiya Luo,
- Baoyong Gong,
- Jin Li,
- Juan Feng,
- Hui Zhang,
- Weiwei Qi,
- Ti Zhou
- Published: August 5, 2021
- https://doi.org/10.1371/journal.pbio.3001348