Synaptotagmin-7–mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants

Qiu-Wen Wang; Ying-Han Wang; Bing Wang; Yun Chen; Si-Yao Lu; Jun Yao

doi:10.1371/journal.pbio.3001323

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Synaptotagmin-7–mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants

Qiu-Wen Wang,

Roles Formal analysis, Investigation, Methodology, Project administration

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Ying-Han Wang,

Roles Investigation, Methodology

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Bing Wang,

Roles Investigation, Methodology

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Yun Chen,

Roles Investigation, Methodology

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China

https://orcid.org/0000-0002-8708-7799

⨯
Si-Yao Lu,

Roles Investigation, Methodology

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China

https://orcid.org/0000-0002-8278-2696

⨯
Jun Yao

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: jyao@mail.tsinghua.edu.cn

Affiliation State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, IDG/McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing, China

https://orcid.org/0000-0002-4916-3412

⨯

Synaptotagmin-7–mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants

Qiu-Wen Wang,
Ying-Han Wang,
Bing Wang,
Yun Chen,
Si-Yao Lu,
Jun Yao

Published: July 6, 2021
https://doi.org/10.1371/journal.pbio.3001323

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