RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity

• Martina Proietti Onori,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands, The ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus Medical Center, Rotterdam, the Netherlands

  https://orcid.org/0000-0003-0360-2894

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• Linda M. C. Koene ,

  Contributed equally to this work with: Linda M. C. Koene, Carmen B. Schäfer

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands, The ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus Medical Center, Rotterdam, the Netherlands

  https://orcid.org/0000-0001-6482-9473

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• Carmen B. Schäfer ,

  Contributed equally to this work with: Linda M. C. Koene, Carmen B. Schäfer

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands

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• Mark Nellist,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Zuid Holland, the Netherlands

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• Marcel de Brito van Velze,

  Roles Software, Writing – review & editing

  Affiliation Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands

  https://orcid.org/0000-0003-1185-2076

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• Zhenyu Gao,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands

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• Ype Elgersma ,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

  * E-mail: y.elgersma@erasmusmc.nl (YE); g.vanwoerden@erasmumc.nl (GMvW)

  Affiliations Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands, The ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus Medical Center, Rotterdam, the Netherlands, Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Zuid Holland, the Netherlands

  https://orcid.org/0000-0002-3758-1297

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• Geeske M. van Woerden

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: y.elgersma@erasmusmc.nl (YE); g.vanwoerden@erasmumc.nl (GMvW)

  Affiliations Department of Neuroscience, Erasmus Medical Center, Rotterdam, the Netherlands, The ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus Medical Center, Rotterdam, the Netherlands, Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Zuid Holland, the Netherlands

  https://orcid.org/0000-0003-2492-9239

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