Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies

• Xing Zhu ,

  Contributed equally to this work with: Xing Zhu, Dhiraj Mannar, Shanti S. Srivastava, Alison M. Berezuk

  Roles Conceptualization, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-4839-4857

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• Dhiraj Mannar ,

  Contributed equally to this work with: Xing Zhu, Dhiraj Mannar, Shanti S. Srivastava, Alison M. Berezuk

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0002-7154-8677

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• Shanti S. Srivastava ,

  Contributed equally to this work with: Xing Zhu, Dhiraj Mannar, Shanti S. Srivastava, Alison M. Berezuk

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0002-4208-6127

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• Alison M. Berezuk ,

  Contributed equally to this work with: Xing Zhu, Dhiraj Mannar, Shanti S. Srivastava, Alison M. Berezuk

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-8512-0180

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• Jean-Philippe Demers,

  Roles Conceptualization, Data curation, Formal analysis, Visualization, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-9875-4473

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• James W. Saville,

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-8813-721X

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• Karoline Leopold,

  Roles Conceptualization, Methodology, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0001-5904-5076

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• Wei Li,

  Roles Formal analysis, Writing – original draft

  Affiliation Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0002-6960-7404

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• Dimiter S. Dimitrov,

  Roles Methodology, Resources

  Affiliation Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0002-2258-1024

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• Katharine S. Tuttle,

  Roles Data curation, Methodology

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0002-9788-1830

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• Steven Zhou,

  Roles Methodology

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

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• Sagar Chittori,

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-1417-6552

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• Sriram Subramaniam

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sriram.subramaniam@ubc.ca

  Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-4231-4115

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