Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio

• Isaac J. T. Strong ,

  Roles Data curation, Investigation, Methodology, Visualization, Writing – original draft

  ¶‡ These authors share first authorship on this work.

  Affiliation Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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• Xiaoyun Lei ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization

  ¶‡ These authors share first authorship on this work.

  Affiliation Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China

  ⨯
• Fang Chen,

  Roles Investigation, Methodology

  Affiliation Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China

  ⨯
• Kai Yuan ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yuankai@csu.edu.cn

  Affiliations Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, China, Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China

  https://orcid.org/0000-0001-7002-5703

  ⨯
• Patrick H. O’Farrell

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0003-0011-2734

  ⨯