Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission

• Dong Ma,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – original draft

  Affiliations Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Medical University, Shijiazhuang, China, School of Public Health, North China University of Science and Technology, Tangshan, China

  http://orcid.org/0000-0001-8288-4775

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• Bin Zheng,

  Roles Methodology, Project administration

  Affiliation Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Medical University, Shijiazhuang, China

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• He-liang Liu,

  Roles Funding acquisition, Project administration, Resources

  Affiliation School of Public Health, North China University of Science and Technology, Tangshan, China

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• Yong-bo Zhao,

  Roles Data curation, Investigation, Resources

  Affiliation Department of Cardiac surgery, the Fourth Hospital of Hebei Medical University, Shi Jiazhuang, China

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• Xiao Liu,

  Roles Data curation, Formal analysis, Investigation, Resources

  Affiliation Department of Cardiac surgery, the Fourth Hospital of Hebei Medical University, Shi Jiazhuang, China

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• Xin-hua Zhang,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization

  Affiliation Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Medical University, Shijiazhuang, China

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• Qiang Li,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Medical University, Shijiazhuang, China

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• Wei-bo Shi,

  Roles Investigation, Resources

  Affiliation Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, Shijiazhuang, China

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• Toru Suzuki,

  Roles Supervision, Validation, Visualization

  Affiliation Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom

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• Jin-kun Wen

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: wjk@hebmu.edu.cn

  Affiliation Department of Biochemistry and Molecular Biology, Key Laboratory of Neural and Vascular Biology, Ministry of Education, Hebei Medical University, Shijiazhuang, China

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