Generation and validation of versatile inducible CRISPRi embryonic stem cell and mouse model

• Rui Li ,

  Contributed equally to this work with: Rui Li, Xianyou Xia, Xing Wang

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

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• Xianyou Xia ,

  Contributed equally to this work with: Rui Li, Xianyou Xia, Xing Wang

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

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• Xing Wang ,

  Contributed equally to this work with: Rui Li, Xianyou Xia, Xing Wang

  Roles Formal analysis, Methodology

  Affiliation State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

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• Xiaoyu Sun,

  Roles Formal analysis, Methodology

  Affiliation State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

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• Zhongye Dai,

  Roles Methodology

  Affiliation State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China

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• Dawei Huo,

  Roles Methodology

  Affiliations State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China, Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China

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• Huimin Zheng,

  Roles Methodology

  Affiliation Department of Prosthodontics, School and Hospital of Stomatology, Tianjin Medical University, Tianjin, China

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• Haiqing Xiong,

  Roles Methodology

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

  https://orcid.org/0000-0002-1260-2426

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• Aibin He,

  Roles Methodology

  Affiliation Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

  https://orcid.org/0000-0002-3489-2305

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• Xudong Wu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – review & editing

  * E-mail: wuxudong@tmu.edu.cn

  Affiliations State Key Laboratory of Experimental Hematology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Cellular Homeostasis and Human Diseases, Department of Cell Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China, Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China, Tianjin Key Laboratory of Epigenetics for Organ Development of Premature Infants, Tianjin, China

  https://orcid.org/0000-0001-9594-479X

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