Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

• Emmanuel A. Asante ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: e.asante@prion.ucl.ac.uk (EAA); j.wadsworth@prion.ucl.ac.uk (JDFW); jc@prion.ucl.ac.uk (JC)

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

  http://orcid.org/0000-0003-3771-4843

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• Jacqueline M. Linehan,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Andrew Tomlinson,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Tatiana Jakubcova,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Shyma Hamdan,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Andrew Grimshaw,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Michelle Smidak,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Asif Jeelani,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

  http://orcid.org/0000-0001-9618-7639

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• Akin Nihat,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

  http://orcid.org/0000-0003-2892-1402

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• Simon Mead,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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• Sebastian Brandner,

  Roles Formal analysis, Writing – review & editing

  Affiliations MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology and Division of Neuropathology, the National Hospital For Neurology and Neurosurgery, University College London NHS Foundation Trust, Queen Square, London United Kingdom

  http://orcid.org/0000-0002-9821-0342

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• Jonathan D. F. Wadsworth ,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  * E-mail: e.asante@prion.ucl.ac.uk (EAA); j.wadsworth@prion.ucl.ac.uk (JDFW); jc@prion.ucl.ac.uk (JC)

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

  http://orcid.org/0000-0002-4797-2259

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• John Collinge

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Writing – original draft, Writing – review & editing

  * E-mail: e.asante@prion.ucl.ac.uk (EAA); j.wadsworth@prion.ucl.ac.uk (JDFW); jc@prion.ucl.ac.uk (JC)

  Affiliation MRC Prion Unit at UCL, UCL Institute of Prion Diseases, London, United Kingdom

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