Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

• Johannes Kettunen ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland, National Institute for Health and Welfare, Helsinki, Finland

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• Michael V. Holmes ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations Medical Research Council Population Health Research Unit, University of Oxford, Oxford, United Kingdom, Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom, National Institute for Health Research, Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, United Kingdom, Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom

  http://orcid.org/0000-0001-6617-0879

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• Elias Allara ,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-1634-8330

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• Olga Anufrieva ,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliation Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland

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• Pauli Ohukainen,

  Roles Conceptualization, Writing – review & editing

  Affiliation Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland

  http://orcid.org/0000-0002-0919-7204

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• Clare Oliver-Williams,

  Roles Formal analysis, Writing – review & editing

  Affiliations British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, Homerton College, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-3573-2426

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• Qin Wang,

  Roles Methodology, Writing – review & editing

  Affiliation Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland

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• Therese Tillin,

  Roles Writing – review & editing

  Affiliation Institute of Cardiovascular Science, University College London, London, United Kingdom

  ⨯
• Alun D. Hughes,

  Roles Writing – review & editing

  Affiliation Institute of Cardiovascular Science, University College London, London, United Kingdom

  http://orcid.org/0000-0001-5432-5271

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• Mika Kähönen,

  Roles Writing – review & editing

  Affiliation Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland

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• Terho Lehtimäki,

  Roles Writing – review & editing

  Affiliation Department of Clinical Chemistry, Fimlab Laboratories, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland

  ⨯
• Jorma Viikari,

  Roles Writing – review & editing

  Affiliations Department of Medicine, University of Turku, Turku, Finland, Division of Medicine, Turku University Hospital, Turku, Finland

  ⨯
• Olli T. Raitakari,

  Roles Writing – review & editing

  Affiliations Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland, Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland

  ⨯
• Veikko Salomaa,

  Roles Writing – review & editing

  Affiliation National Institute for Health and Welfare, Helsinki, Finland

  http://orcid.org/0000-0001-7563-5324

  ⨯
• Marjo-Riitta Järvelin,

  Roles Writing – review & editing

  Affiliations Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland, Biocenter Oulu, University of Oulu, Oulu, Finland, Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland, Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, United Kingdom

  http://orcid.org/0000-0002-2149-0630

  ⨯
• Markus Perola,

  Roles Writing – review & editing

  Affiliations National Institute for Health and Welfare, Helsinki, Finland, Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland, Estonian Genome Center, University of Tartu, Tartu, Estonia

  ⨯
• George Davey Smith,

  Roles Methodology, Writing – review & editing

  Affiliations Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, Population Health Science, Bristol Medical School, University of Bristol, Bristol, United Kingdom

  http://orcid.org/0000-0002-1407-8314

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• Nish Chaturvedi,

  Roles Writing – review & editing

  Affiliation Institute of Cardiovascular Science, University College London, London, United Kingdom

  ⨯
• John Danesh,

  Roles Writing – review & editing

  Affiliations British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, United Kingdom, British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Emanuele Di Angelantonio ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Adam S. Butterworth ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, United Kingdom

  http://orcid.org/0000-0002-6915-9015

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•  [ ... ],
• Mika Ala-Korpela

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: mika.ala-korpela@oulu.fi

  ¶‡ JK, MVH, EA, and OA are joint first authors on this work. ED, ASB, and MAK are joint senior authors on this work.

  Affiliations Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland, Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, Population Health Science, Bristol Medical School, University of Bristol, Bristol, United Kingdom, NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland, Systems Epidemiology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University, Melbourne, Victoria, Australia

  http://orcid.org/0000-0001-5905-1206

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