Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms

• Idan Frumkin ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: frumkin.idan@gmail.com (IF); pilpel@weizmann.ac.il (YP)

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  http://orcid.org/0000-0003-4944-3374

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• Ido Yofe,

  Roles Conceptualization, Data curation, Investigation, Methodology

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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• Raz Bar-Ziv ,

  Contributed equally to this work with: Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek

  Roles Data curation, Methodology

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  http://orcid.org/0000-0003-2615-1942

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• Yonat Gurvich ,

  Contributed equally to this work with: Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek

  Roles Data curation, Methodology

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  ⨯
• Yen-Yun Lu ,

  Contributed equally to this work with: Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek

  Roles Data curation, Formal analysis, Methodology, Resources

  Affiliation Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany

  http://orcid.org/0000-0002-6818-9028

  ⨯
• Yoav Voichek ,

  Contributed equally to this work with: Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek

  Roles Formal analysis, Methodology

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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• Ruth Towers,

  Roles Data curation

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  http://orcid.org/0000-0001-6167-7590

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• Dvir Schirman,

  Roles Data curation, Formal analysis

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  http://orcid.org/0000-0001-5175-0176

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• Heike Krebber,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Abteilung für Molekulare Genetik, Institut für Mikrobiologie und Genetik, Göttinger Zentrum für Molekulare Biowissenschaften (GZMB), Georg-August Universität Göttingen, Göttingen, Germany

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• Yitzhak Pilpel

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: frumkin.idan@gmail.com (IF); pilpel@weizmann.ac.il (YP)

  Affiliation Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

  http://orcid.org/0000-0003-3200-9344

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