A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion

• Emily Z. Guo ,

  Contributed equally to this work with: Emily Z. Guo, Daniel C. Desrosiers

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

  ⨯
• Daniel C. Desrosiers ,

  Contributed equally to this work with: Emily Z. Guo, Daniel C. Desrosiers

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

  ⨯
• Jan Zalesak,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Molecular Biotechnology (IMBA), Vienna Biocenter (VBC), Vienna, Austria

  ⨯
• James Tolchard,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Institute of Chemistry and Biology of Membranes and Nano-objects, CBMN-CNRS Université de Bordeaux, Pessac, France

  http://orcid.org/0000-0002-5779-4935

  ⨯
• Mélanie Berbon,

  Roles Investigation, Writing – review & editing

  Affiliation Institute of Chemistry and Biology of Membranes and Nano-objects, CBMN-CNRS Université de Bordeaux, Pessac, France

  ⨯
• Birgit Habenstein,

  Roles Formal analysis, Investigation, Supervision, Writing – review & editing

  Affiliation Institute of Chemistry and Biology of Membranes and Nano-objects, CBMN-CNRS Université de Bordeaux, Pessac, France

  http://orcid.org/0000-0003-3723-9552

  ⨯
• Thomas Marlovits,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Institute of Molecular Biotechnology (IMBA), Vienna Biocenter (VBC), Vienna, Austria, Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria, Center for Structural Systems Biology (CSSB), University Medical Center Hamburg-Eppendorf (UKE) and German Electron Synchrotron Centre (DESY), Hamburg, Germany

  ⨯
• Antoine Loquet,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Institute of Chemistry and Biology of Membranes and Nano-objects, CBMN-CNRS Université de Bordeaux, Pessac, France

  http://orcid.org/0000-0001-7176-7813

  ⨯
• Jorge E. Galán

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jorge.galan@yale.edu

  Affiliation Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

  http://orcid.org/0000-0002-6531-0355

  ⨯