ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology

• Yongliang Cao ,

  Contributed equally to this work with: Yongliang Cao, Haochen Xu, Yuanbo Zhu

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Haochen Xu ,

  Contributed equally to this work with: Yongliang Cao, Haochen Xu, Yuanbo Zhu

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Yuanbo Zhu ,

  Contributed equally to this work with: Yongliang Cao, Haochen Xu, Yuanbo Zhu

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Mei-Juan Shi,

  Roles Data curation, Methodology

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Lixiang Wei,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Jin Zhang,

  Roles Formal analysis, Software

  Affiliation High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui, China

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• Shuo Cheng,

  Roles Data curation, Methodology

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Yiqian Shi,

  Roles Data curation

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Haiyang Tong,

  Roles Data curation, Formal analysis, Software

  Affiliation High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui, China

  ⨯
• Lijing Kang,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Lu Lu,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Haiyu Luo,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Xing Yang,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Xiaofei Bai,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

  ⨯
• Ranran Wang,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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• Yuanyuan Ma,

  Roles Data curation, Formal analysis

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

  ⨯
• Yun Wang,

  Roles Methodology, Validation

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

  ⨯
• Zhongfeng Wang,

  Roles Methodology, Validation

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

  ⨯
• Kai Zhong ,

  Roles Methodology, Software, Validation

  * E-mail: wenyingf@fudan.edu.cn (WF); bingqiaoz@fudan.edu.cn (BQZ); kzhong@hmfl.ac.cn (KZ)

  Affiliations High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui, China, Neurodegenerative Disease Research Center, School of Life Sciences, University of Science and Technology of China, CAS Key Laboratory of Brain Functions and Disease, Hefei, China

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• Bing-Qiao Zhao ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: wenyingf@fudan.edu.cn (WF); bingqiaoz@fudan.edu.cn (BQZ); kzhong@hmfl.ac.cn (KZ)

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

  http://orcid.org/0000-0002-6155-0618

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•  [ ... ],
• Wenying Fan

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: wenyingf@fudan.edu.cn (WF); bingqiaoz@fudan.edu.cn (BQZ); kzhong@hmfl.ac.cn (KZ)

  Affiliation Department of Translational Neuroscience, Jing’an District Centre Hospital of Shanghai, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China

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