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Open Access
Peer-reviewed
Research Article
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
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Lihong Zhan,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Grietje Krabbe,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Fei Du,
Roles Formal analysis, Methodology, Software, Visualization
Affiliation Department of Geography, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Ian Jones,
Roles Formal analysis, Software
Affiliation Institute for Human Genetics and Department of Neurology, University of California-San Francisco, San Francisco, California, United States of America
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Meredith C. Reichert,
Roles Conceptualization, Data curation, Formal analysis, Investigation
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Maria Telpoukhovskaia,
Roles Formal analysis, Methodology, Software
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Lay Kodama,
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Neuroscience Graduate Program, University of California, San Francisco, California, United States of America
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Chao Wang,
Roles Resources
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Seo-hyun Cho,
Roles Data curation, Formal analysis, Investigation, Visualization
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Faten Sayed,
Roles Resources, Writing – review & editing
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Yaqiao Li,
Roles Data curation, Resources
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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David Le,
Roles Resources
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Yungui Zhou,
Roles Resources
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America
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Yin Shen,
Roles Resources
Affiliation Institute for Human Genetics and Department of Neurology, University of California-San Francisco, San Francisco, California, United States of America
⨯ - Brian West,
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Li Gan
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: lig2033@med.cornell.edu
Affiliations Gladstone Institutes of Neurological Disease, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America, Helen and Robert Appel Alzheimer’s Disease Institute, Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York, United States of America
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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
- Lihong Zhan,
- Grietje Krabbe,
- Fei Du,
- Ian Jones,
- Meredith C. Reichert,
- Maria Telpoukhovskaia,
- Lay Kodama,
- Chao Wang,
- Seo-hyun Cho,
- Faten Sayed
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- Published: February 8, 2019
- https://doi.org/10.1371/journal.pbio.3000134
- See the preprint