Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

Pierre Raia; Marta Carroni; Etienne Henry; Gérard Pehau-Arnaudet; Sébastien Brûlé; Pierre Béguin; Ghislaine Henneke; Erik Lindahl; Marc Delarue; Ludovic Sauguet

doi:10.1371/journal.pbio.3000122

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Open Access

Peer-reviewed

Research Article

Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

Pierre Raia,

Roles Conceptualization, Investigation, Writing – original draft

Affiliations Unit of Structural Dynamics of Macromolecules, Pasteur Institute and CNRS UMR 3528, Paris, France, Sorbonne Université, Ecole Doctorale Complexité du Vivant (ED515), Paris, France

http://orcid.org/0000-0003-3469-1922

⨯
Marta Carroni,

Roles Investigation

Affiliation Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Sweden

http://orcid.org/0000-0002-7697-6427

⨯
Etienne Henry,

Roles Investigation

Affiliation CNRS, IFREMER, Univ Brest, Laboratoire de Microbiologie des Environnements Extrêmes, Plouzané, France
⨯
Gérard Pehau-Arnaudet,

Roles Investigation

Affiliation Utech UBI, Pasteur Institute and CNRS UMR 3528, Paris, France
⨯
Sébastien Brûlé,

Roles Investigation

Affiliation Molecular Biophysics Platform, Pasteur Institute, C2RT and CNRS UMR 3528, Paris, France

http://orcid.org/0000-0002-8797-6748

⨯
Pierre Béguin,

Roles Investigation

Affiliation Unit of Molecular Biology of Gene in Extremophiles, Pasteur Institute, Paris, France
⨯
Ghislaine Henneke,

Roles Investigation, Supervision

Affiliation IFREMER, CNRS, Univ Brest, Laboratoire de Microbiologie des Environnements Extrêmes, Plouzané, France
⨯
Erik Lindahl,

Roles Investigation

Affiliation Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Sweden
⨯
Marc Delarue ,

Roles Funding acquisition, Resources, Supervision

* E-mail: ludovic.sauguet@pasteur.fr (LS); marc.delarue@pasteur.fr (MD)

Affiliation Unit of Structural Dynamics of Macromolecules, Pasteur Institute and CNRS UMR 3528, Paris, France
⨯
Ludovic Sauguet

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: ludovic.sauguet@pasteur.fr (LS); marc.delarue@pasteur.fr (MD)

Affiliation Unit of Structural Dynamics of Macromolecules, Pasteur Institute and CNRS UMR 3528, Paris, France

http://orcid.org/0000-0002-1259-6601

⨯

Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

Pierre Raia,
Marta Carroni,
Etienne Henry,
Gérard Pehau-Arnaudet,
Sébastien Brûlé,
Pierre Béguin,
Ghislaine Henneke,
Erik Lindahl,
Marc Delarue,
Ludovic Sauguet

Published: January 18, 2019
https://doi.org/10.1371/journal.pbio.3000122

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