Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells

• Teresa Buenaventura,

  Roles Investigation, Methodology

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Stavroula Bitsi,

  Roles Investigation, Methodology

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  ⨯
• William E. Laughlin,

  Roles Investigation, Methodology

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

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• Thomas Burgoyne,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Department of Cell Biology, Institute of Ophthalmology, University College London, London, United Kingdom

  http://orcid.org/0000-0002-8428-720X

  ⨯
• Zekun Lyu,

  Roles Investigation

  Affiliations Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom, Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

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• Affiong I. Oqua,

  Roles Investigation

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0002-0584-120X

  ⨯
• Hannah Norman,

  Roles Investigation

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0001-9877-137X

  ⨯
• Emma R. McGlone,

  Roles Investigation

  Affiliation Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0002-0968-6972

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• Andrey S. Klymchenko,

  Roles Resources

  Affiliation Laboratoire de Bioimagerie et Pathologies, UMR CNRS 7021, University of Strasbourg, Illkirch-Strasbourg, France

  http://orcid.org/0000-0002-2423-830X

  ⨯
• Ivan R. Corrêa Jr,

  Roles Resources

  Affiliation New England Biolabs, Ipswich, Massachusetts, United States of America

  http://orcid.org/0000-0002-3169-6878

  ⨯
• Abigail Walker,

  Roles Investigation

  Affiliation Department of Surgery and Cancer, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0001-6729-2034

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• Asuka Inoue,

  Roles Resources

  Affiliation Tohoku University, Sendai, Japan

  ⨯
• Aylin Hanyaloglu,

  Roles Methodology, Resources, Software, Writing – review & editing

  Affiliation Department of Surgery and Cancer, Imperial College London, London, United Kingdom

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• Jak Grimes,

  Roles Investigation

  Affiliations Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom, Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham and Nottingham, United Kingdom

  http://orcid.org/0000-0001-8992-8224

  ⨯
• Zsombor Koszegi,

  Roles Formal analysis, Investigation, Visualization

  Affiliations Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom, Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham and Nottingham, United Kingdom

  ⨯
• Davide Calebiro,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, United Kingdom, Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham and Nottingham, United Kingdom

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• Guy A. Rutter,

  Roles Funding acquisition, Resources

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Stephen R. Bloom,

  Roles Funding acquisition, Resources

  Affiliation Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0003-1542-2348

  ⨯
• Ben Jones ,

  Contributed equally to this work with: Ben Jones, Alejandra Tomas

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: a.tomas-catala@imperial.ac.uk (AT); ben.jones@imperial.ac.uk (BJ)

  Affiliation Section of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0003-0461-2584

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•  [ ... ],
• Alejandra Tomas

  Contributed equally to this work with: Ben Jones, Alejandra Tomas

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: a.tomas-catala@imperial.ac.uk (AT); ben.jones@imperial.ac.uk (BJ)

  Affiliation Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0002-2290-8453

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