MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis

• Dan Xu ,

  Contributed equally to this work with: Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck

  Roles Data curation, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China, College of Biological Science and Engineering, Institute of Life Sciences, Fuzhou University, Fuzhou, China

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• Minghui Yao ,

  Contributed equally to this work with: Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck

  Roles Data curation, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Yaqing Wang ,

  Contributed equally to this work with: Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck

  Roles Investigation, Methodology, Resources, Supervision

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Ling Yuan ,

  Contributed equally to this work with: Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck

  Roles Data curation, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China

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• Joerg D. Hoeck ,

  Contributed equally to this work with: Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck

  Roles Investigation, Methodology, Resources

  Affiliation CR-UK London Research Institute, London, United Kingdom

  ⨯
• Jingwen Yu,

  Roles Investigation

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Liang Liu,

  Roles Methodology

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

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• Yvonne Y. C. Yeap,

  Roles Methodology

  Affiliation School of Biomedical Science, Faculty of Medicine, University of Queensland, St Lucia, Australia

  ⨯
• Weiya Zhang,

  Roles Investigation

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Feng Zhang,

  Roles Investigation, Methodology

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

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• Yinghang Feng,

  Roles Methodology

  Affiliation Sino-Danish College, University of Chinese Academy of Science, Beijing, China

  ⨯
• Tiantian Ma,

  Roles Methodology

  Affiliation State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

  ⨯
• Yujie Wang,

  Roles Methodology

  Affiliation College of Biological Science and Engineering, Institute of Life Sciences, Fuzhou University, Fuzhou, China

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• Dominic C. H. Ng,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation School of Biomedical Science, Faculty of Medicine, University of Queensland, St Lucia, Australia

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• Xiaoyin Niu,

  Roles Resources

  Affiliation Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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• Bing Su,

  Roles Funding acquisition, Resources

  Affiliations Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Axel Behrens ,

  Roles Resources, Supervision

  * E-mail: zhxu@genetics.ac.cn (ZX); axel.behrens@crick.ac.uk (AB)

  Affiliations Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom, King’s College London, Faculty of Life Sciences and Medicine, Guy’s Campus, London, United Kingdom

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•  [ ... ],
• Zhiheng Xu

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: zhxu@genetics.ac.cn (ZX); axel.behrens@crick.ac.uk (AB)

  Affiliations State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China, Sino-Danish College, University of Chinese Academy of Science, Beijing, China, Parkinson’s Disease Center, Beijing Institute for Brain Disorders, Beijing, China

  http://orcid.org/0000-0002-4809-2851

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