The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability

Pierre A. Haas; Stephanie S. M. H. Höhn; Aurelia R. Honerkamp-Smith; Julius B. Kirkegaard; Raymond E. Goldstein

doi:10.1371/journal.pbio.2005536

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Peer-reviewed

Research Article

The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability

Pierre A. Haas ,

Contributed equally to this work with: Pierre A. Haas, Stephanie S. M. H. Höhn

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
⨯
Stephanie S. M. H. Höhn ,

Contributed equally to this work with: Pierre A. Haas, Stephanie S. M. H. Höhn

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
⨯
Aurelia R. Honerkamp-Smith,

Roles Conceptualization, Formal analysis, Methodology, Software, Visualization, Writing – review & editing

Affiliations Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom, Department of Physics, Lehigh University, Bethlehem, Pennsylvania, United States of America
⨯
Julius B. Kirkegaard,

Roles Formal analysis, Methodology, Software, Writing – review & editing

Affiliation Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
⨯
Raymond E. Goldstein

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: R.E.Goldstein@damtp.cam.ac.uk

Affiliation Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom

http://orcid.org/0000-0003-2645-0598

⨯

The noisy basis of morphogenesis: Mechanisms and mechanics of cell sheet folding inferred from developmental variability

Pierre A. Haas,
Stephanie S. M. H. Höhn,
Aurelia R. Honerkamp-Smith,
Julius B. Kirkegaard,
Raymond E. Goldstein

Published: July 12, 2018
https://doi.org/10.1371/journal.pbio.2005536

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