Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

• Audrey P. Gasch ,

  Contributed equally to this work with: Audrey P. Gasch, Feiqiao Brian Yu

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

  * E-mail: agasch@wisc.edu

  ¶‡ These authors share first authorship on this work.

  Affiliations Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Great Lakes Bioenergy Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

  http://orcid.org/0000-0002-8182-257X

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• Feiqiao Brian Yu ,

  Contributed equally to this work with: Audrey P. Gasch, Feiqiao Brian Yu

  Roles Methodology

  ¶‡ These authors share first authorship on this work.

  Affiliation Department of Bioengineering, Stanford University, Stanford, California, United States of America

  ⨯
• James Hose,

  Roles Investigation, Methodology, Validation

  Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

  ⨯
• Leah E. Escalante,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

  ⨯
• Mike Place,

  Roles Methodology, Visualization

  Affiliation Great Lakes Bioenergy Research Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

  ⨯
• Rhonda Bacher,

  Roles Formal analysis, Investigation

  Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Jad Kanbar,

  Roles Methodology

  Current address: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

  Affiliation Department of Bioengineering, Stanford University, Stanford, California, United States of America

  ⨯
• Doina Ciobanu,

  Roles Methodology

  Affiliation Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America

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• Laura Sandor,

  Roles Methodology

  Affiliation Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America

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• Igor V. Grigoriev,

  Roles Supervision

  Affiliation Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America

  ⨯
• Christina Kendziorski,

  Roles Supervision

  Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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• Stephen R. Quake,

  Roles Supervision

  Affiliations Department of Bioengineering, Stanford University, Stanford, California, United States of America, Chan Zuckerberg Biohub, San Francisco, California, United States of America

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• Megan N. McClean

  Roles Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Biomedical Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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