Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain

• Yu-Ting Chou,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan, Institute of Biotechnology, National Tsing-Hua University, Hsinchu, Taiwan

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• Jeng-Kai Jiang,

  Roles Conceptualization, Resources

  Affiliation Division of Colon and Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan

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• Muh-Hwa Yang,

  Roles Conceptualization, Resources

  Affiliation Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan

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• Jeng-Wei Lu,

  Roles Investigation, Methodology

  Affiliations Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan, Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan

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• Hua-Kuo Lin,

  Roles Investigation, Methodology

  Affiliation Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan

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• Horng-Dar Wang ,

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: chyuh@nhri.org.tw (CHY); hdwang@life.nthu.edu.tw (HDW)

  Affiliation Institute of Biotechnology, National Tsing-Hua University, Hsinchu, Taiwan

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• Chiou-Hwa Yuh

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: chyuh@nhri.org.tw (CHY); hdwang@life.nthu.edu.tw (HDW)

  Affiliations Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan, Institute of Bioinformatics and Structural Biology, National Tsing-Hua University, Hsinchu, Taiwan, Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan

  http://orcid.org/0000-0002-2356-1551

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