Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Yuhong Han; Yue Xiong; Xuanming Shi; Jiang Wu; Yun Zhao; Jin Jiang

doi:10.1371/journal.pbio.2002063

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Open Access

Peer-reviewed

Research Article

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Yuhong Han,

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

http://orcid.org/0000-0001-8933-4637

⨯
Yue Xiong,

Roles Data curation, Formal analysis, Investigation

Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institute of Life Sciences, CAS, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
⨯
Xuanming Shi,

Roles Data curation, Formal analysis, Investigation, Resources

Affiliation Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
⨯
Jiang Wu,

Roles Resources, Supervision

Affiliation Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
⨯
Yun Zhao ,

Roles Resources, Supervision

* E-mail: jin.jiang@utsouthwestern.edu (JJ); yunzhao@sibcb.ac.cn (YZ)

Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institute of Life Sciences, CAS, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
⨯
Jin Jiang

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: jin.jiang@utsouthwestern.edu (JJ); yunzhao@sibcb.ac.cn (YZ)

Affiliations Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America, Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America
⨯

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Yuhong Han,
Yue Xiong,
Xuanming Shi,
Jiang Wu,
Yun Zhao,
Jin Jiang

Published: August 4, 2017
https://doi.org/10.1371/journal.pbio.2002063

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Medulloblastoma
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Cilia
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Gene expression
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