The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans

• Carol M. Manhart,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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• Xiaodan Ni,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

  ⨯
• Martin A. White,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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• Joaquin Ortega,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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• Jennifer A. Surtees,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Biochemistry, University at Buffalo, State University of New York, Buffalo, New York, United States of America

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• Eric Alani

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: eea3@cornell.edu

  Affiliation Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

  http://orcid.org/0000-0002-5011-9339

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