Inefficiencies and Patient Burdens in the Development of the Targeted Cancer Drug Sorafenib: A Systematic Review

• James Mattina,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Studies of Translation, Ethics and Medicine (STREAM), Biomedical Ethics Unit, McGill University, Montréal, Quebec, Canada

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• Benjamin Carlisle,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Studies of Translation, Ethics and Medicine (STREAM), Biomedical Ethics Unit, McGill University, Montréal, Quebec, Canada

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• Yasmina Hachem,

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Studies of Translation, Ethics and Medicine (STREAM), Biomedical Ethics Unit, McGill University, Montréal, Quebec, Canada

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• Dean Fergusson,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Clinical Epidemiology, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

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• Jonathan Kimmelman

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jonathan.kimmelman@mcgill.ca

  Affiliation Studies of Translation, Ethics and Medicine (STREAM), Biomedical Ethics Unit, McGill University, Montréal, Quebec, Canada

  http://orcid.org/0000-0003-1614-6779

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