The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

• Rita Machado de Oliveira ,

  Contributed equally to this work with: Rita Machado de Oliveira, Hugo Vicente Miranda

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal

  ⨯
• Hugo Vicente Miranda ,

  Contributed equally to this work with: Rita Machado de Oliveira, Hugo Vicente Miranda

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal

  http://orcid.org/0000-0001-8065-9259

  ⨯
• Laetitia Francelle,

  Roles Investigation, Validation, Visualization

  Affiliation Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany

  ⨯
• Raquel Pinho,

  Roles Investigation

  Affiliations Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany, Faculty of Medicine, University of Porto, Porto, Portugal

  ⨯
• Éva M. Szegö,

  Roles Investigation

  Affiliation Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany

  ⨯
• Renato Martinho,

  Roles Investigation

  Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Francesca Munari,

  Roles Investigation

  Affiliations Department for NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany

  ⨯
• Diana F. Lázaro,

  Roles Investigation

  Affiliation Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany

  ⨯
• Sébastien Moniot,

  Roles Investigation

  Affiliation Department of Biochemistry, University of Bayreuth, Bayreuth, Germany

  ⨯
• Patrícia Guerreiro,

  Roles Investigation

  Affiliation Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany

  ⨯
• Luis Fonseca,

  Roles Investigation

  Affiliation Department for NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

  ⨯
• Zrinka Marijanovic,

  Roles Investigation

  Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Pedro Antas,

  Roles Investigation

  Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Ellen Gerhardt,

  Roles Investigation

  Affiliation Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany

  ⨯
• Francisco Javier Enguita,

  Roles Investigation, Resources

  Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Bruno Fauvet,

  Roles Methodology, Resources

  Affiliation Laboratory of Molecular and Chemical Biology of Neurodegeneration, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland

  ⨯
• Deborah Penque,

  Roles Investigation, Resources

  Affiliation Laboratório de Proteómica, Departamento de Genética Humana, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisboa, Portugal

  ⨯
• Teresa Faria Pais,

  Roles Investigation

  Affiliation Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal

  ⨯
• Qiang Tong,

  Roles Investigation, Resources

  Affiliation USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

  ⨯
• Stefan Becker,

  Roles Investigation

  Affiliation Department for NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

  ⨯
• Sebastian Kügler,

  Roles Investigation, Resources

  Affiliation Department of Neurology, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany

  ⨯
• Hilal Ahmed Lashuel,

  Roles Investigation, Resources

  Affiliation Laboratory of Molecular and Chemical Biology of Neurodegeneration, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland

  ⨯
• Clemens Steegborn,

  Roles Conceptualization, Investigation, Resources, Validation, Writing – review & editing

  Affiliation Department of Biochemistry, University of Bayreuth, Bayreuth, Germany

  ⨯
• Markus Zweckstetter,

  Roles Conceptualization, Investigation, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Department for NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany, Department of Neurology, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany

  ⨯
•  [ ... ],
• Tiago Fleming Outeiro

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: touteir@gwdg.de

  Affiliations CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal, Department of Neurodegeneration and Restorative Research, University Medical Center Göttingen, Göttingen, Germany, Max Planck Institute for Experimental Medicine, Göttingen, Germany, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany

  ⨯
• [ view all ]
• [ view less ]