Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects

• Rosaysela Santos ,

  Contributed equally to this work with: Rosaysela Santos, Shimako Kawauchi

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations Department of Developmental and Cell Biology, University of California, Irvine, California, United States of America, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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• Shimako Kawauchi ,

  Contributed equally to this work with: Rosaysela Santos, Shimako Kawauchi

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations Department of Developmental and Cell Biology, University of California, Irvine, California, United States of America, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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• Russell E. Jacobs,

  Roles Investigation, Methodology, Resources

  Affiliation Biological Imaging Center, Beckman Institute, California Institute of Technology, Pasadena, California, United States of America

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• Martha E. Lopez-Burks,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliations Department of Developmental and Cell Biology, University of California, Irvine, California, United States of America, Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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• Hojae Choi,

  Roles Formal analysis, Investigation, Visualization

  Affiliation Center for Complex Biological Systems, University of California, Irvine, California, United States of America

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• Jamie Wikenheiser,

  Roles Investigation, Methodology

  Affiliation Department of Anatomy and Neurobiology, University of California, Irvine, California, United States of America

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• Benedikt Hallgrimsson,

  Roles Conceptualization, Investigation, Methodology, Resources

  Affiliation Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada

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• Heather A. Jamniczky,

  Roles Investigation, Methodology, Visualization

  Affiliation Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada

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• Scott E. Fraser,

  Roles Conceptualization, Methodology, Resources

  Affiliation Departments of Biology and Bioengineering, University of Southern California, Los Angeles, California, United States of America

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• Arthur D. Lander ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: adlander@uci.edu (ADL); alcalof@uci.edu (ALC)

  Affiliations Center for Complex Biological Systems, University of California, Irvine, California, United States of America, Biological Imaging Center, Beckman Institute, California Institute of Technology, Pasadena, California, United States of America

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• Anne L. Calof

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: adlander@uci.edu (ADL); alcalof@uci.edu (ALC)

  Affiliations Department of Developmental and Cell Biology, University of California, Irvine, California, United States of America, Center for Complex Biological Systems, University of California, Irvine, California, United States of America, Department of Anatomy and Neurobiology, University of California, Irvine, California, United States of America

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