The Structure of an NDR/LATS Kinase–Mob Complex Reveals a Novel Kinase–Coactivator System and Substrate Docking Mechanism

• Gergő Gógl ,

  Contributed equally to this work with: Gergő Gógl, Kyle D. Schneider

  Affiliations Lendület Protein Interaction Group, Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary, Department of Biochemistry, Eötvös Loránd University, Budapest, Hungary

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• Kyle D. Schneider ,

  Contributed equally to this work with: Gergő Gógl, Kyle D. Schneider

  Affiliation Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

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• Brian J. Yeh,

  Affiliation Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

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• Nashida Alam,

  Affiliation Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

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• Alex N. Nguyen Ba,

  Affiliation Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada

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• Alan M. Moses,

  Affiliation Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada

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• Csaba Hetényi,

  Affiliation MTA-ELTE Molecular Biophysics Research Group, Eötvös Loránd University, Hungarian Academy of Sciences, Budapest, Hungary

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• Attila Reményi ,

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Lendület Protein Interaction Group, Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary

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• Eric L. Weiss

  * E-mail: elweiss@northwestern.edu

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

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