Structure-Guided Design of Selective Epac1 and Epac2 Agonists

• Frank Schwede,

  Affiliation BIOLOG Life Science Institute, Bremen, Germany

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• Daniela Bertinetti,

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

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• Carianne N. Langerijs,

  Affiliation Galapagos BV, CR Leiden, The Netherlands

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• Michael A. Hadders,

  Affiliation Department of Chemistry, Laboratory of Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands

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• Hans Wienk,

  Affiliation Department of Chemistry, NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands

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• Johanne H. Ellenbroek,

  Affiliation Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands

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• Eelco J. P. de Koning,

  Affiliations Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands, Hubrecht Institute/KNAW and University Medical Center Utrecht, Utrecht, The Netherlands

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• Johannes L. Bos,

  Affiliation Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, UMC Utrecht, Utrecht, The Netherlands

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• Friedrich W. Herberg,

  Affiliation Department of Biochemistry, University of Kassel, Kassel, Germany

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• Hans-Gottfried Genieser,

  Affiliation BIOLOG Life Science Institute, Bremen, Germany

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• Richard A. J. Janssen,

  Affiliation Galapagos BV, CR Leiden, The Netherlands

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• Holger Rehmann

  * E-mail: h.rehmann@UMCutrecht.nl

  Affiliation Molecular Cancer Research and Cancer Genomics Netherlands, Center for Molecular Medicine, UMC Utrecht, Utrecht, The Netherlands

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