Thermodynamic System Drift in Protein Evolution

• Kathryn M. Hart,

  Affiliations Department of Chemistry, University of California, Berkeley, Berkeley, California, United States of America, Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, United States of America

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• Michael J. Harms,

  Affiliation Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America

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• Bryan H. Schmidt,

  Current address: Department of Biochemistry and Biophysics, University of San Francisco School of Medicine, San Francisco, California, United States of America

  Affiliations Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, United States of America, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, California, United States of America

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• Carolyn Elya,

  Affiliations Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, United States of America, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, California, United States of America

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• Joseph W. Thornton,

  Affiliation Department of Human Genetics and Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America

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• Susan Marqusee

  * E-mail: marqusee@berkeley.edu

  Affiliations Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, California, United States of America, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, California, United States of America

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