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Open Access
Peer-reviewed
Research Article
JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation
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Feng Wang,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Lin He,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Peiwei Huangyang,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Jing Liang,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Wenzhe Si,
Affiliations Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China
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Ruorong Yan,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Xiao Han,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Shumeng Liu,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Bin Gui,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Wanjin Li,
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Di Miao,
Affiliation Proteomics Facility, School of Life Sciences, Tsinghua University, Beijing, China
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Chao Jing,
Affiliation State Key Laboratory of Molecular Oncology, The Cancer Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
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Zhihua Liu,
Affiliation State Key Laboratory of Molecular Oncology, The Cancer Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
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Fei Pei,
Affiliation Department of Pathology, Peking University Health Science Center, Beijing, China
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Luyang Sun ,
* E-mail: luyang_sun@hsc.pku.edu.cn (L.S.); yshang@hsc.pku.edu.cn (Y.S.)
Affiliation Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China
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Yongfeng Shang
* E-mail: luyang_sun@hsc.pku.edu.cn (L.S.); yshang@hsc.pku.edu.cn (Y.S.)
Affiliations Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing, China, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, China
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JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation
- Feng Wang,
- Lin He,
- Peiwei Huangyang,
- Jing Liang,
- Wenzhe Si,
- Ruorong Yan,
- Xiao Han,
- Shumeng Liu,
- Bin Gui,
- Wanjin Li
- Published: March 25, 2014
- https://doi.org/10.1371/journal.pbio.1001819