Reduction of the Cholesterol Sensor SCAP in the Brains of Mice Causes Impaired Synaptic Transmission and Altered Cognitive Function

Open Access

Peer-reviewed

Research Article

Ryo Suzuki ,

Contributed equally to this work with: Ryo Suzuki, Heather A. Ferris

Current address: The University of Tokyo, Tokyo, Japan

Affiliation Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Heather A. Ferris ,

Contributed equally to this work with: Ryo Suzuki, Heather A. Ferris

Affiliation Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Melissa J. Chee,

Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Eleftheria Maratos-Flier,

Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
C. Ronald Kahn

* E-mail: c.ronald.kahn@joslin.harvard.edu

Affiliation Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Cholesterol
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Diabetes mellitus
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Mouse models
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Mice
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Gene expression
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Hippocampus
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Cognitive impairment
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Synapses
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