Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains

• Chen Wang ,

  Contributed equally to this work with: Chen Wang, Jiayan Sang

  Affiliations State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China, Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, United States of America

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• Jiayan Sang ,

  Contributed equally to this work with: Chen Wang, Jiayan Sang

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Jiawei Wang,

  Affiliation Department of Biology and Technology, Tsinghua University, Beijing, China

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• Mingyan Su,

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Jennifer S. Downey,

  Affiliation Division of Biomedical Science, Herman Ostrow School of Dentistry of University of Southern California, Los Angeles, California, United States of America

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• Qinggan Wu,

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Shida Wang,

  Affiliation Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada

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• Yongfei Cai,

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Xiaozheng Xu,

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Jun Wu,

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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• Dilani B. Senadheera,

  Affiliation Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada

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• Dennis G. Cvitkovitch,

  Affiliation Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada

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• Lin Chen,

  Affiliation Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, United States of America

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• Steven D. Goodman,

  Affiliation Division of Biomedical Science, Herman Ostrow School of Dentistry of University of Southern California, Los Angeles, California, United States of America

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• Aidong Han

  * E-mail: ahan@xmu.edu.cn

  Affiliation State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiangan, Xiamen, China

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