Niche-Associated Activation of Rac Promotes the Asymmetric Division of Drosophila Female Germline Stem Cells

Wen Lu; M. Olivia Casanueva; Anthony P. Mahowald; Mihoko Kato; David Lauterbach; Edwin L. Ferguson

doi:10.1371/journal.pbio.1001357

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Research Article

Niche-Associated Activation of Rac Promotes the Asymmetric Division of Drosophila Female Germline Stem Cells

Wen Lu ,

Contributed equally to this work with: Wen Lu, M. Olivia Casanueva

Current address: Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

Affiliation Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America
⨯
M. Olivia Casanueva ,

Contributed equally to this work with: Wen Lu, M. Olivia Casanueva

Current address: Centre for Genomic Regulation, Barcelona, Spain

Affiliation Committee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, Illinois, United States of America
⨯
Anthony P. Mahowald,

Affiliations Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America, Committee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, Illinois, United States of America, Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America
⨯
Mihoko Kato,

Current address: Department of Biology, California Institute of Technology, Pasadena, California, United States of America

Affiliation Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America
⨯
David Lauterbach,

Current address: College of Medicine, University of Illinois at Peoria, Peoria, Illinois, United Sates of America

Affiliation Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America
⨯
Edwin L. Ferguson

* E-mail: elfergus@uchicago.edu

Affiliations Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America, Committee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, Illinois, United States of America, Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America
⨯

Niche-Associated Activation of Rac Promotes the Asymmetric Division of Drosophila Female Germline Stem Cells

Wen Lu,
M. Olivia Casanueva,
Anthony P. Mahowald,
Mihoko Kato,
David Lauterbach,
Edwin L. Ferguson

Published: July 3, 2012
https://doi.org/10.1371/journal.pbio.1001357

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BMP signaling
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Cell cycle and cell division
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Germ cells
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