p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

Abhinav K. Jain; Kendra Allton; Michelina Iacovino; Elisabeth Mahen; Robert J. Milczarek; Thomas P. Zwaka; Michael Kyba; Michelle Craig Barton

doi:10.1371/journal.pbio.1001268

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Peer-reviewed

Research Article

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

Abhinav K. Jain,

Affiliation Program in Genes and Development, Center for Stem Cell and Development Biology, Department of Biochemistry and Molecular Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Kendra Allton,

Affiliation Program in Genes and Development, Center for Stem Cell and Development Biology, Department of Biochemistry and Molecular Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michelina Iacovino,

Affiliation Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Elisabeth Mahen,

Affiliation Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Robert J. Milczarek,

Affiliation Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Thomas P. Zwaka,

Affiliation Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Michael Kyba,

Affiliation Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Michelle Craig Barton

* E-mail: mbarton@mdanderson.org

Affiliation Program in Genes and Development, Center for Stem Cell and Development Biology, Department of Biochemistry and Molecular Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

Abhinav K. Jain,
Kendra Allton,
Michelina Iacovino,
Elisabeth Mahen,
Robert J. Milczarek,
Thomas P. Zwaka,
Michael Kyba,
Michelle Craig Barton

Published: February 28, 2012
https://doi.org/10.1371/journal.pbio.1001268

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Cell differentiation
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Small interfering RNA
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Cell cycle and cell division
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Transfection
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MicroRNAs
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Pluripotency
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Gene expression
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