HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer

• Merel Gijsen,

  Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

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• Peter King,

  Affiliation Oncology Discovery Research and Early Development, Johnson & Johnson Pharmaceutical Research and Development, Janssen Pharmaceutica, Beerse, Belgium

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• Tim Perera,

  Affiliation Oncology Discovery Research and Early Development, Johnson & Johnson Pharmaceutical Research and Development, Janssen Pharmaceutica, Beerse, Belgium

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• Peter J. Parker,

  Affiliations Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom, Division of Cancer Studies, King's College School of Medicine, Guy's Hospital, London, United Kingdom

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• Adrian L. Harris,

  Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

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• Banafshé Larijani,

  Affiliation Cell Biophysics Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom

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• Anthony Kong

  * E-mail: Anthony.kong@imm.ox.ac.uk

  Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

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