The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion

Open Access

Peer-reviewed

Research Article

Marcia N. Paddock,

Affiliations Department of Immunology, University of Washington, Seattle, Washington, United States of America, Center for Immunity and Immunotherapies, Seattle Children's Hospital Research Institute, Seattle, Washington, United States of America
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Ben D. Buelow,

Affiliations Department of Immunology, University of Washington, Seattle, Washington, United States of America, Center for Immunity and Immunotherapies, Seattle Children's Hospital Research Institute, Seattle, Washington, United States of America
⨯
Shunichi Takeda,

Affiliation Crest Laboratory, Department of Radiation Genetics, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan
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Andrew M. Scharenberg

* E-mail: andrewms@u.washington.edu

Affiliations Department of Immunology, University of Washington, Seattle, Washington, United States of America, Center for Immunity and Immunotherapies, Seattle Children's Hospital Research Institute, Seattle, Washington, United States of America
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DNA repair
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Point mutation
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Genetic loci
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Mutation
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DNA damage
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B cells
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Protein domains
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Gene conversion
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