Inherent Dynamics of the Acid-Sensing Ion Channel 1 Correlates with the Gating Mechanism

• Huaiyu Yang ,

  Contributed equally to this work with: Huaiyu Yang, Ye Yu

  Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Ye Yu ,

  Contributed equally to this work with: Huaiyu Yang, Ye Yu

  Affiliation Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Wei-Guang Li,

  Affiliation Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Fang Yu,

  Affiliation Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Hui Cao,

  Affiliation Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Tian-Le Xu ,

  * E-mail: tlxu@ion.ac.cn (T-LX); hljiang@mail.shcnc.ac.cn (HJ)

  Affiliation Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Hualiang Jiang

  * E-mail: tlxu@ion.ac.cn (T-LX); hljiang@mail.shcnc.ac.cn (HJ)

  Affiliations Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, School of Pharmacy, East China University of Science and Technology, Shanghai, China

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