Tissue-Specific Genetic Control of Splicing: Implications for the Study of Complex Traits

Erin L Heinzen; Dongliang Ge; Kenneth D Cronin; Jessica M Maia; Kevin V Shianna; Willow N Gabriel; Kathleen A Welsh-Bohmer; Christine M Hulette; Thomas N Denny; David B Goldstein

doi:10.1371/journal.pbio.1000001

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Open Access

Peer-reviewed

Research Article

Tissue-Specific Genetic Control of Splicing: Implications for the Study of Complex Traits

Erin L Heinzen ,

Contributed equally to this work with: Erin L Heinzen, Dongliang Ge

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Dongliang Ge ,

Contributed equally to this work with: Erin L Heinzen, Dongliang Ge

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Kenneth D Cronin,

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Jessica M Maia,

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Kevin V Shianna,

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Willow N Gabriel,

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯
Kathleen A Welsh-Bohmer,

Affiliation Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University, Durham, North Carolina, United States of America
⨯
Christine M Hulette,

Affiliation Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University, Durham, North Carolina, United States of America
⨯
Thomas N Denny,

Affiliation Human Vaccine Institute, Duke University, Durham, North Carolina, United States of America
⨯
David B Goldstein

*To whom correspondence should be addressed. E-mail: d.goldstein@duke.edu

Affiliation Institute for Genome Sciences & Policy, Center for Human Genome Variation, Duke University, Durham, North Carolina, United States of America
⨯

Tissue-Specific Genetic Control of Splicing: Implications for the Study of Complex Traits

Erin L Heinzen,
Dongliang Ge,
Kenneth D Cronin,
Jessica M Maia,
Kevin V Shianna,
Willow N Gabriel,
Kathleen A Welsh-Bohmer,
Christine M Hulette,
Thomas N Denny,
David B Goldstein

Published: December 23, 2008
https://doi.org/10.1371/journal.pbio.1000001

Reader Comments (3)

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13 Jun 2012
15:07 GMT
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New address for this resource Posted by MaryM on 13 Jun 2012 at 15:07 GMT
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12 Jul 2011
13:06 GMT
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Expression data released to GEO Posted by eheinzen on 12 Jul 2011 at 13:06 GMT
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07 May 2009
22:28 GMT
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Case-control data suggests that the type 1 diabetes association and the co-localized RPS26 splicing signal are independent Posted by PLOSBiology on 07 May 2009 at 22:28 GMT

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Single nucleotide polymorphisms
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Gene expression
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Alternative splicing
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