Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

• Laurent Kappeler ,

  Contributed equally to this work with: Laurent Kappeler, Carlos De Magalhaes Filho

  Affiliation INSERM U893, Hôpital Saint-Antoine, Paris, France

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• Carlos De Magalhaes Filho ,

  Contributed equally to this work with: Laurent Kappeler, Carlos De Magalhaes Filho

  Affiliations INSERM U893, Hôpital Saint-Antoine, Paris, France , Université Pierre-et-Marie-Curie, Paris, France

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• Joëlle Dupont,

  Affiliation INRA, Nouzilly, France

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• Patricia Leneuve,

  Affiliation INSERM U893, Hôpital Saint-Antoine, Paris, France

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• Pascale Cervera,

  Affiliation Service d'Anatomopathologie, Hôpital Saint-Antoine, Paris, France

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• Laurence Périn,

  Affiliation INSERM U893, Hôpital Saint-Antoine, Paris, France

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• Catherine Loudes,

  Affiliation INSERM U549, Centre Paul Broca, Paris, France

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• Annick Blaise,

  Affiliations INSERM U893, Hôpital Saint-Antoine, Paris, France , Université Pierre-et-Marie-Curie, Paris, France

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• Rüdiger Klein,

  Affiliation Department of Molecular Neurobiology, Max-Planck Institute of Neurobiology, Munich-Martinsried, Germany

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• Jacques Epelbaum,

  Affiliation INSERM U549, Centre Paul Broca, Paris, France

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• Yves Le Bouc,

  Affiliations INSERM U893, Hôpital Saint-Antoine, Paris, France , Université Pierre-et-Marie-Curie, Paris, France

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• Martin Holzenberger

  *To whom correspondence should be addressed. E-mail: martin.holzenberger@inserm.fr

  Affiliation INSERM U893, Hôpital Saint-Antoine, Paris, France

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