Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch

• Jun Lu,

  Affiliations Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Mischa Machius,

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Irina Dulubova,

  Affiliations Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Han Dai,

  Affiliations Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Thomas C Südhof,

  Affiliations Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Diana R Tomchick,

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Josep Rizo

  *To whom correspondence should be addressed. E-mail: jose@arnie.swmed.edu

  Affiliations Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America , Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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