Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor Dysfunction

• Dominique Helmlinger,

  ¤ Current address: Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  Affiliation Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France

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• Sara Hardy ,

  Contributed equally to this work with: Sara Hardy, Gretta Abou-Sleymane

  Affiliation Department of Transcription, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France

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• Gretta Abou-Sleymane ,

  Contributed equally to this work with: Sara Hardy, Gretta Abou-Sleymane

  Affiliations Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France, Chaire de Génétique Humaine, Collège de France, Paris, France

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• Adrien Eberlin,

  Affiliation Department of Transcription, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France

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• Aaron B Bowman,

  Affiliation Howard Hughes Medical Institute, Department of Molecular and Human Genetics, and Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

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• Anne Gansmüller,

  Affiliation Imaging Technology Platform, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Strasbourg, France

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• Serge Picaud,

  Affiliation Laboratoire de Physiopathologie Cellulaire et Moléculaire de la Rétine, INSERM U-592, UPMC, Paris, France

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• Huda Y Zoghbi,

  Affiliation Howard Hughes Medical Institute, Department of Molecular and Human Genetics, and Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

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• Yvon Trottier,

  Affiliations Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France, Chaire de Génétique Humaine, Collège de France, Paris, France

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• Làszlò Tora ,

  *To whom correspondence should be addressed. E-mail: devys@igbmc.u-strasbg.fr (LT), Email: laszlo@igbmc.u-strasbg.fr (DD)

  Affiliation Department of Transcription, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France

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• Didier Devys

  *To whom correspondence should be addressed. E-mail: devys@igbmc.u-strasbg.fr (LT), Email: laszlo@igbmc.u-strasbg.fr (DD)

  Affiliations Department of Molecular Pathology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France, Department of Transcription, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France

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