Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

• Haitao Yang,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Weiqing Xie,

  Affiliation State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China

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• Xiaoyu Xue,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Kailin Yang,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Jing Ma,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Wenxue Liang,

  Affiliation Shanghai Institute of Hematology, Rui-Jin Hospital affiliated to Shanghai Second Medical University, Shanghai, China

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• Qi Zhao,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Zhe Zhou,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Duanqing Pei,

  Affiliation Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

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• John Ziebuhr,

  Affiliation Institute of Virology and Immunology, University of Würzburg, Würzburg, Germany

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• Rolf Hilgenfeld,

  Affiliation Institute for Biochemistry, University of Lübeck, Lübeck, Germany

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• Kwok Yung Yuen,

  Affiliation Department of Microbiology, University of Hong Kong, Hong Kong, China

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• Luet Wong,

  Affiliation Department of Chemistry, Inorganic Chemistry Laboratory, University of Oxford, Oxford, United Kingdom

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• Guangxia Gao,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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• Saijuan Chen,

  Affiliation Shanghai Institute of Hematology, Rui-Jin Hospital affiliated to Shanghai Second Medical University, Shanghai, China

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• Zhu Chen,

  Affiliation Shanghai Institute of Hematology, Rui-Jin Hospital affiliated to Shanghai Second Medical University, Shanghai, China

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• Dawei Ma ,

  *To whom correspondence should be addressed. E-mail: madw@mail.sioc.ac.cn (DM), Email: raozh@xtal.tsinghua.edu.cn (ZR)

  Affiliation State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China

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• Mark Bartlam,

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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•  [ ... ],
• Zihe Rao

  *To whom correspondence should be addressed. E-mail: madw@mail.sioc.ac.cn (DM), Email: raozh@xtal.tsinghua.edu.cn (ZR)

  Affiliations Tsinghua-IBP Joint Research Group for Structural Biology, Tsinghua University, Beijing, China, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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