Engineering a Dimeric Caspase-9: A Re-evaluation of the Induced Proximity Model for Caspase Activation

• Yang Chao ,

  Contributed equally to this work with: Yang Chao, Eric N Shiozaki

  Affiliation Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, New Jersey, United States of America

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• Eric N Shiozaki ,

  Contributed equally to this work with: Yang Chao, Eric N Shiozaki

  Affiliation Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, New Jersey, United States of America

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• Srinivasa M Srinivasula,

  Affiliation Laboratory of Immune Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Daniel J Rigotti,

  Affiliation Department of Biology, Haverford College, Haverford, Pennsylvania, United States of America

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• Robert Fairman,

  Affiliation Department of Biology, Haverford College, Haverford, Pennsylvania, United States of America

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• Yigong Shi

  *To whom correspondence should be addressed. E-mail: yshi@molbio.princeton.edu

  Affiliation Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, New Jersey, United States of America

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